Citigroup Biomedical Imaging Center

CBIC Publications 2020-2021

[⁶⁸Ga]-DOTATATE PET/MRI as an adjunct imaging modality for radiation treatment planning of meningiomas.

Mahase SS, Roth O'Brien DA, No D, Roytman M, Skafida ME, Lin E, Karakatsanis NA, Osborne JR, Brandmaier A, Pannullo SC, Ramakrishna R, Stieg PE, Knisely JPS, Ivanidze J.Neurooncol Adv. 2021 Jan 21;3(1):vdab012. doi: 10.1093/noajnl/vdab012. eCollection 2021 Jan-Dec.PMID: 33738446 Free PMC article.

[⁸⁹Zr]Zr-huJ591 immuno-PET targeting PSMA in IDH mutant anaplastic oligodendroglioma.

Krebs S, Grommes C, McDevitt MR, Carlin SD, O'Donoghue JA, Graham MS, Young RJ, Schöder H, Gutin PH, Bander NH, Osborne JR.Eur J Nucl Med Mol Imaging. 2021 Sep 8. doi: 10.1007/s00259-021-05543-5. Online ahead of print.PMID: 34498111 No abstract available.

Alpha radioimmunotherapy using ²²⁵Ac-proteus-DOTA for solid tumors - safety at curative doses.

Cheal SM, McDevitt MR, Santich BH, Patel M, Yang G, Fung EK, Veach DR, Bell M, Ahad A, Vargas DB, Punzalan B, Pillarsetty NVK, Xu H, Guo HF, Monette S, Michel AO, Piersigilli A, Scheinberg DA, Ouerfelli O, Cheung NV, Larson SM.Theranostics. 2020 Sep 14;10(25):11359-11375. doi: 10.7150/thno.48810. eCollection 2020.PMID: 33052220 Free PMC article. 

Association of Reproductive History With Brain MRI Biomarkers of Dementia Risk in Midlife.

Schelbaum E, Loughlin L, Jett S, Zhang C, Jang G, Malviya N, Hristov H, Pahlajani S, Isaacson R, Dyke JP, Kamel H, Brinton RD, Mosconi L.Neurology. 2021 Dec 7;97(23):e2328-e2339. doi: 10.1212/WNL.0000000000012941. Epub 2021 Nov 3.PMID: 34732544 

A Conversation Between Joseph Osborne and Thomas Hope.

Osborne JR, Hope TA.J Nucl Med. 2020 Sep;61(9):1275-1277. doi: 10.2967/jnumed.120.255141.PMID: 32873736 Free article. No abstract available.

The effect of calcar femoral neck plating on vascularity of the femoral head and neck.

Kubik JF, Bornes TD, Klinger CE, Dyke JP, Helfet DL.Bone Jt Open. 2021 Aug;2(8):611-617. doi: 10.1302/2633-1462.28.BJO-2021-0099.R1.PMID: 34378395 Free PMC article.

Effects of Ibudilast on MRI Measures in the Phase 2 SPRINT-MS Study.

Naismith RT, Bermel RA, Coffey CS, Goodman AD, Fedler J, Kearney M, Klawiter EC, Nakamura K, Narayanan S, Goebel C, Yankey J, Klingner E, Fox RJ; SPRINT-MS investigators.Neurology. 2021 Jan 26;96(4):e491-e500. doi: 10.1212/WNL.0000000000011314. Epub 2020 Dec 2.PMID: 33268562 Clinical Trial.

The effects of dual plating on the vascularity of the distal femur.

Rollick NC, Gadinsky NE, Klinger CE, Kubik JF, Dyke JP, Helfet DL, Wellman DS.Bone Joint J. 2020 Apr;102-B(4):530-538. doi: 10.1302/0301-620X.102B4.BJJ-2019-1776.PMID: 32228080

Endosteal Vasculature Dominates Along the Tibial Cortical Diaphysis: A Quantitative Magnetic Resonance Imaging Analysis.

Levack AE, Klinger C, Gadinsky NE, Dyke JP, Fung MM, Helfet DL, Lorich DG.J Orthop Trauma. 2020 Dec 1;34(12):662-668. doi: 10.1097/BOT.0000000000001853.PMID: 33079848 Free PMC article.

George de Hevesy in America.

Klingensmith WC 3rd, Osborne JR.J Nucl Med. 2020 Feb;61(2):304-305. doi: 10.2967/jnumed.119.233254. Epub 2019 Jul 13.PMID: 31302636 No abstract available.

Heuristic scoring method utilizing FDG-PET statistical parametric mapping in the evaluation of suspected Alzheimer disease and frontotemporal lobar degeneration.

Ford JN, Sweeney EM, Skafida M, Glynn S, Amoashiy M, Lange DJ, Lin E, Chiang GC, Osborne JR, Pahlajani S, de Leon MJ, Ivanidze J.Am J Nucl Med Mol Imaging. 2021 Aug 15;11(4):313-326. eCollection 2021.PMID: 34513285 Free PMC article.

Imaging expression of prostate-specific membrane antigen and response to PSMA-targeted β-emitting radionuclide therapies in metastatic castration-resistant prostate cancer.

Vlachostergios PJ, Niaz MJ, Skafida M, Mosallaie SA, Thomas C, Christos PJ, Osborne JR, Molina AM, Nanus DM, Bander NH, Tagawa ST.Prostate. 2021 Apr;81(5):279-285. doi: 10.1002/pros.24104. Epub 2021 Jan 19.PMID: 33465252 Clinical Trial.

Increased Vascularity in the Neonatal versus Adult Meniscus: Evaluation with Magnetic Resonance Imaging.

Lin KM, Gadinsky NE, Klinger CE, Dyke JP, Rodeo SA, Green DW, Fabricant PD, Helfet DL, Shea KG, Lazaro LE.Cartilage. 2021 Dec;13(2_suppl):1562S-1569S. doi: 10.1177/1947603520923143. Epub 2020 May 23.PMID: 32447965 

IntraOmmaya compartmental radioimmunotherapy using ¹³¹I-omburtamab-pharmacokinetic modeling to optimize therapeutic index.

Yerrabelli RS, He P, Fung EK, Kramer K, Zanzonico PB, Humm JL, Guo H, Pandit-Taskar N, Larson SM, Cheung NV.Eur J Nucl Med Mol Imaging. 2021 Apr;48(4):1166-1177. doi: 10.1007/s00259-020-05050-z. Epub 2020 Oct 13.PMID: 33047248

Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis.

Chandler CS, Bell MM, Chung SK, Veach DR, Fung EK, Punzalan B, Burnes Vargas D, Patel M, Xu H, Guo HF, Santich BH, Zanzonico PB, Monette S, Nash GM, Cercek A, Jungbluth A, Pandit-Taskar N, Cheung NKV, Larson SM, Cheal SM.Mol Cancer Ther. 2021 Oct 19. doi: 10.1158/1535-7163.MCT-21-0353. Online ahead of print.PMID: 34667111

Is it time to switch your T1W sequence? Assessing the impact of prospective motion correction on the reliability and quality of structural imaging.

Ai L, Craddock RC, Tottenham N, Dyke JP, Lim R, Colcombe S, Milham M, Franco AR.Neuroimage. 2021 Feb 1;226:117585. doi: 10.1016/j.neuroimage.2020.117585. Epub 2020 Nov 26.PMID: 33248256 Free PMC article.

Molecular Imaging of Striatal Dopaminergic Neuronal Loss and the Neurovascular Unit in Parkinson Disease.

Ivanidze J, Skafida M, Pandya S, Patel D, Osborne JR, Raj A, Gupta A, Henchcliffe C, Dyke JP.Front Neurosci. 2020 Sep 18;14:528809. doi: 10.3389/fnins.2020.528809. eCollection 2020.PMID: 33071729 Free PMC article.

MRI characterization of early CNS transport kinetics post intrathecal gadolinium injection: Trends of subarachnoid and parenchymal distribution in healthy volunteers.

Dyke JP, Xu HS, Verma A, Voss HU, Chazen JL.Clin Imaging. 2020 Dec;68:1-6. doi: 10.1016/j.clinimag.2020.04.043. Epub 2020 May 16.PMID: 32544736

Phase I trial of docetaxel plus lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 (¹⁷⁷Lu-J591) for metastatic castration-resistant prostate cancer.

Batra JS, Niaz MJ, Whang YE, Sheikh A, Thomas C, Christos P, Vallabhajosula S, Jhanwar YS, Molina AM, Nanus DM, Osborne JR, Bander NH, Tagawa ST.Urol Oncol. 2020 Nov;38(11):848.e9-848.e16. doi: 10.1016/j.urolonc.2020.05.028. Epub 2020 Jun 27.PMID: 32600929 Clinical Trial.

A pilot study treatment of malignant tumors using low-dose ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG).

Paul DM, Ghiuzeli CM, Rini J, Palestro CJ, Fung EK, Ghali M, Ben-Levi E, Prideaux A, Vallabhajosula S, Popa EC.Am J Nucl Med Mol Imaging. 2020 Dec 15;10(6):334-341. eCollection 2020.PMID: 33329935 Free PMC article.

Pilot Study of Hyperfractionated Dosing of Lutetium-177-Labeled Antiprostate-Specific Membrane Antigen Monoclonal Antibody J591 (¹⁷⁷ Lu-J591) for Metastatic Castration-Resistant Prostate Cancer.

Niaz MJ, Batra JS, Walsh RD, Ramirez-Fort MK, Vallabhajosula S, Jhanwar YS, Molina AM, Nanus DM, Osborne JR, Bander NH, Tagawa ST.Oncologist. 2020 Jun;25(6):477-e895. doi: 10.1634/theoncologist.2020-0028. Epub 2020 Jan 30.PMID: 31999003 Free PMC article.

Preclinical Evaluation of a High-Affinity Sarcophagine-Containing PSMA Ligand for ⁶⁴Cu/⁶⁷Cu-Based Theranostics in Prostate Cancer.

Kelly JM, Ponnala S, Amor-Coarasa A, Zia NA, Nikolopoulou A, Williams C Jr, Schlyer DJ, DiMagno SG, Donnelly PS, Babich JW.Mol Pharm. 2020 Jun 1;17(6):1954-1962. doi: 10.1021/acs.molpharmaceut.0c00060. Epub 2020 May 4.PMID: 32286841

Presynaptic dopamine deficit in minimally conscious state patients following traumatic brain injury.

Fridman EA, Osborne JR, Mozley PD, Victor JD, Schiff ND.Brain. 2019 Jul 1;142(7):1887-1893. doi: 10.1093/brain/awz118.PMID: 31505542 Free PMC article. Clinical Trial.

Prostate-Specific Membrane Antigen Positron Emission Tomography and the New Algorithm for Patients With Prostate Cancer Prior to Prostatectomy.

Osborne JR, Bander NH, Tagawa ST.JAMA Oncol. 2021 Nov 1;7(11):1642-1643. doi: 10.1001/jamaoncol.2021.3762.PMID: 34529003 No abstract available.

Prostate-Specific Membrane Antigen Uptake and Survival in Metastatic Castration-Resistant Prostate Cancer.

Vlachostergios PJ, Niaz MJ, Sun M, Mosallaie SA, Thomas C, Christos PJ, Osborne JR, Molina AM, Nanus DM, Bander NH, Tagawa ST.Front Oncol. 2021 Feb 18;11:630589. doi: 10.3389/fonc.2021.630589. eCollection 2021.PMID: 33680970 Free PMC article.

Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates.

Ballon DJ, Rosenberg JB, Fung EK, Nikolopoulou A, Kothari P, De BP, He B, Chen A, Heier LA, Sondhi D, Kaminsky SM, Mozley PD, Babich JW, Crystal RG.Hum Gene Ther. 2020 Dec;31(23-24):1237-1259. doi: 10.1089/hum.2020.116.

Quantitative assessment of the vascularity of the skeletally immature patella: a cadaveric study using MRI.

Gadinsky NE, Lin KM, Klinger CE, Dyke JP, Kleeblad LJ, Shea KG, Helfet DL, Rodeo SA, Green DW, Lazaro LE.J Child Orthop. 2021 Apr 19;15(2):157-165. doi: 10.1302/1863-2548.15.200261.PMID: 34040662 Free PMC article.

Quantitative MRI Proton Density Fat Fraction: A Coming of Age.

Dyke JP.Radiology. 2021 Mar;298(3):652-653. doi: 10.1148/radiol.2020204356. Epub 2021 Jan 19.PMID: 33475469 No abstract available.

Radiation segmentectomy of hepatic metastases with Y-90 glass microspheres.

Kurilova I, Bendet A, Fung EK, Petre EN, Humm JL, Boas FE, Crane CH, Kemeny N, Kingham TP, Cercek A, D'Angelica MI, Beets-Tan RGH, Sofocleous CT.Abdom Radiol (NY). 2021 Jul;46(7):3428-3436. doi: 10.1007/s00261-021-02956-6. Epub 2021 Feb 19.PMID: 33606062

Review of commonly used prostate specific PET tracers used in prostate cancer imaging in current clinical practice.

Niaz MJ, Sun M, Skafida M, Niaz MO, Ivanidze J, Osborne JR, O'Dwyer E.Clin Imaging. 2021 Nov;79:278-288. doi: 10.1016/j.clinimag.2021.06.006. Epub 2021 Jun 24.PMID: 34182326 Review.

Safety of Direct Intraparenchymal AAVrh.10-Mediated Central Nervous System Gene Therapy for Metachromatic Leukodystrophy.

Rosenberg JB, Chen A, De BP, Dyke JP, Ballon DJ, Monette S, Ricart Arbona RJ, Kaminsky SM, Crystal RG, Sondhi D.Hum Gene Ther. 2021 Jun;32(11-12):563-580. doi: 10.1089/hum.2020.269. Epub 2021 Mar 30.PMID: 33380277

A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy.

Santich BH, Cheal SM, Ahmed M, McDevitt MR, Ouerfelli O, Yang G, Veach DR, Fung EK, Patel M, Burnes Vargas D, Malik AA, Guo HF, Zanzonico PB, Monette S, Michel AO, Rudin CM, Larson SM, Cheung NK.Clin Cancer Res. 2021 Jan 15;27(2):532-541. doi: 10.1158/1078-0432.CCR-20-2150. Epub 2020 Sep 21.PMID: 32958698 Free PMC article.

A simple strategy to reduce the salivary gland and kidney uptake of PSMA-targeting small molecule radiopharmaceuticals.

Kalidindi TM, Lee SG, Jou K, Chakraborty G, Skafida M, Tagawa ST, Bander NH, Schoder H, Bodei L, Pandit-Taskar N, Lewis JS, Larson SM, Osborne JR, Pillarsetty NVK.Eur J Nucl Med Mol Imaging. 2021 Jul;48(8):2642-2651. doi: 10.1007/s00259-020-05150-w. Epub 2021 Jan 25.PMID: 33495926

Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.

Sondhi D, Kaminsky SM, Hackett NR, Pagovich OE, Rosenberg JB, De BP, Chen A, Van de Graaf B, Mezey JG, Mammen GW, Mancenido D, Xu F, Kosofsky B, Yohay K, Worgall S, Kaner RJ, Souwedaine M, Greenwald BM, Kaplitt M, Dyke JP, Ballon DJ, Heier LA, Kiss S, Crystal RG.Sci Transl Med. 2020 Dec 2;12(572):eabb5413. doi: 10.1126/scitranslmed.abb5413.PMID: 33268510 Free PMC article. Clinical Trial.

Somatostatin receptor-2 negative meningioma: pathologic correlation and imaging implications.

Roytman M, Pisapia DJ, Liechty B, Lin E, Skafida M, Magge RS, Osborne JR, Pannullo SC, Knisely JPS, Ramakrishna R, Ivanidze J.Clin Imaging. 2020 Oct;66:18-22. doi: 10.1016/j.clinimag.2020.04.026. Epub 2020 Apr 25.PMID: 32442855

A suitable time point for quantifying the radiochemical purity of ²²⁵Ac-labeled radiopharmaceuticals.

Kelly JM, Amor-Coarasa A, Sweeney E, Wilson JJ, Causey PW, Babich JW.EJNMMI Radiopharm Chem. 2021 Dec 20;6(1):38. doi: 10.1186/s41181-021-00151-y.PMID: 34928478

A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα).

Kelly JM, Jeitner TM, Ponnala S, Williams C Jr, Nikolopoulou A, DiMagno SG, Babich JW.Mol Imaging Biol. 2021 Oct;23(5):686-696. doi: 10.1007/s11307-021-01593-1. Epub 2021 Mar 15.PMID: 33721173

Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer's Disease.

Tataryn NM, Singh V, Dyke JP, Berk-Rauch HE, Clausen DM, Aronowitz E, Norris EH, Strickland S, Ahn HJ.Neurobiol Aging. 2021 Nov;107:96-108. doi: 10.1016/j.neurobiolaging.2021.07.015. Epub 2021 Jul 28.PMID: 34416494